I developed a very bad rash this week from the sorafenib and saw my oncologist in Grand Junction today. I'm taking a prescription steroid, benadryl, vitamin B-6, as well as a skin creams, all of which already seem to be helping just after the first dose. My oncologist recommended that I go off all the supplements that I'm taking just to make sure it's not interfering with the clinical trial medicine. The rash is not bad enough that I have to quit the sorafenib. They tell me that this rash means that it is working.
I have a red rash on my face, neck, shoulders, chest and back. Fortunately, none of it itches; however, my scalp is tender and does itch as well as a few unmentionable places. I have a sore in my mouth. The palms of my hand and soles of my feet and dry and tender.
If the rash gets worse or doesn't respond to the treatment, I may have to go off the clinical trial drug, until it subsides.
On the up side, I've had more energy since starting the sorafenib. I'm not getting as tired as I was.
If anyone out there has had similar experiences, please let me know.